Existing Wording: When the dose or rate is intended to change over the entire administration period, eg. Tapering dose prescriptions, multiple instances of dosage instructions will need to be supplied to convey the different doses/rates.

Proposed Wording: Add to the comment: another common example in institutional settings is "titration' of an IV medication dose to maintain a specific stated hemodynamic value or range e.g. durg x to be administered to maintain AM (arterial mean) greater than 65.